Response-driven dosing with AUSTEDO1

Dial representing starting dose of 12 mg/day to maximum dose of 48 mg/day. In the pivotal trial, the average dose of AUSTEDO® (deutetrabenazine) tablets was >36 mg/day.

Please see additional dosing and administration information at the bottom of this page.

Increase dose until symptom control is effectively and tolerably achieved1

Start treatment at 12 mg/day

Blue arrow pointing right Blue arrow pointing right

Increase by 6 mg/day weekly1

12 mg
/day

(6 mg BID)

SD

6

SD

6

Week 1

[14 tablets per 7 days]

18 mg
/day

(9 mg BID)

SD

9

SD

9

Week 2

[14 tablets per 7 days]

24 mg/
day

(12 mg BID)

SD

12

SD

12

Week 3

[14 tablets per 7 days]

30 mg/
day

(15 mg BID)

SD

6

SD

6

SD

9

SD

9

Week 4

[28 tablets per 7 days]

36 mg/
day

(18 mg BID)

SD

9

SD

9

SD

9

SD

9

Week 5

[28 tablets per 7 days]

42 mg/
day

(21 mg BID)

SD

9

SD

9

SD

12

SD

12

Week 6

[28 tablets per 7 days]

48 mg/
day

(24 mg BID)

SD

12

SD

12

SD

12

SD

12

Week 7

[28 tablets per 7 days]

AUSTEDO is available in 6-mg, 9-mg, and 12-mg tablets1

6 mg AUSTEDO® (deutetrabenazine) tablet. 9 mg AUSTEDO® (deutetrabenazine) tablet. 12 mg AUSTEDO® (deutetrabenazine) tablet.

Tablets not shown at actual size.

Additional dosing and
administration information1

  • Administer total daily dosages above 6 mg/day in 2 divided doses
  • AUSTEDO should be taken with food
  • AUSTEDO® (deutetrabenazine) tablets should be swallowed whole. Tablets should not be chewed, crushed, or broken
  • Starting dose differs for patients switching from tetrabenazine

REFERENCE: 1. AUSTEDO® (deutetrabenazine) tablets current Prescribing Information. Parsippany, NJ: Teva Neuroscience, Inc.