The impact of tardive dyskinesia (TD) goes far beyond involuntary movements1,2

75% of patients reported that TD severely impacted them socially, physically, and psychologically3


In a survey of 269 patients, the impact of TD on daily living was substantial—even for patients with self-assessed mild/moderate symptoms.4

Social factors2,5

  • Social isolation
  • Fewer employment opportunities

Biological and physical factors2,6,7

  • Pain
  • Dental and gait issues
  • Speech impairment
  • Labored breathing
  • Difficulty eating

Psychological factors3

  • Difficulty focusing
  • Low self-esteem
  • Irritability, frustration, and/or anger
  • Feeling unmotivated
  • Anxiety

Due to the impact of TD, patients reported skipping, stopping, or reducing their antipsychotic medication4

LEARN MORE: EVALUATING THE IMPACT
OF TD

No clinical trials have been conducted to demonstrate that treating TD affects the outcomes on this page.

Watch Amber Hoberg, PMHNP-BC, discuss the importance of assessing and managing TD


Mechanism of Disease:

Learn more about how APD use affects dopamine signaling in TD.7

REFERENCES: 1. Cloud LJ, Zutshi D, Factor SA. Tardive dyskinesia: therapeutic options for an increasingly common disorder. Neurotherapeutics. 2014;11(1):166-176. 2. Yassa R. Functional impairment in tardive dyskinesia: medical and psychosocial dimensions. Acta Psychiatr Scand. 1989;80(1):64-67. 3. Data on file. Parsippany, NJ: Teva Neuroscience, Inc. 4. Jain R, Ayyagari R, King S, Edwards GG, Wilhelm A, Leo S. Impact of tardive dyskinesia on physical, psychological, and social aspects of patient lives: a survey of patients and caregivers in the United States. Presented at: Psych Congress 2021; October 29–November 1, 2021; San Antonio, TX. 5. Ascher-Svanum H, Zhu B, Faries D, Peng X, Kinon BJ, Tohen M. Tardive dyskinesia and the 3-year course of schizophrenia: results from a large, prospective, naturalistic study. J Clin Psychiatry. 2008;69(10):1580-1588. 6. Strassnig M, Rosenfeld A, Harvey PD. Tardive dyskinesia: motor system impairments, cognition and everyday functioning. CNS Spectr. 2018;23(6):370-377. 7. Waln O, Jankovic J. An update on tardive dyskinesia: from phenomenology to treatment. Tremor Other Hyperkinet Mov (N Y). 2013;3:tre-03-161-4138-1. doi:10.7916/D88P5Z71