The impact of tardive dyskinesia (TD) goes far beyond involuntary movements1,2

75% of patients reported that TD severely impacted them socially, physically, and psychologically3

In a survey of 269 patients, the impact of TD on daily living was substantial—even for patients with self-assessed mild/moderate symptoms.4

Social factors2,5

  • Social isolation
  • Fewer employment opportunities

Biological and physical factors2,6,7

  • Pain
  • Dental and gait issues
  • Speech impairment
  • Labored breathing
  • Difficulty eating

Psychological factors3

  • Difficulty focusing
  • Low self-esteem
  • Irritability, frustration, and/or anger
  • Feeling unmotivated
  • Anxiety

Due to the impact of TD, patients reported skipping, stopping, or reducing their antipsychotic medication4


No clinical trials have been conducted to demonstrate that treating TD affects the outcomes on this page.

Watch Amber Hoberg, PMHNP-BC, discuss the importance of assessing and managing TD

Mechanism of Disease:

Learn more about how APD use affects dopamine signaling in TD.7

REFERENCES: 1. Cloud LJ, Zutshi D, Factor SA. Tardive dyskinesia: therapeutic options for an increasingly common disorder. Neurotherapeutics. 2014;11(1):166-176. 2. Yassa R. Functional impairment in tardive dyskinesia: medical and psychosocial dimensions. Acta Psychiatr Scand. 1989;80(1):64-67. 3. Data on file. Parsippany, NJ: Teva Neuroscience, Inc. 4. Jain R, Ayyagari R, King S, Edwards GG, Wilhelm A, Leo S. Impact of tardive dyskinesia on physical, psychological, and social aspects of patient lives: a survey of patients and caregivers in the United States. Presented at: Psych Congress 2021; October 29–November 1, 2021; San Antonio, TX. 5. Ascher-Svanum H, Zhu B, Faries D, Peng X, Kinon BJ, Tohen M. Tardive dyskinesia and the 3-year course of schizophrenia: results from a large, prospective, naturalistic study. J Clin Psychiatry. 2008;69(10):1580-1588. 6. Strassnig M, Rosenfeld A, Harvey PD. Tardive dyskinesia: motor system impairments, cognition and everyday functioning. CNS Spectr. 2018;23(6):370-377. 7. Waln O, Jankovic J. An update on tardive dyskinesia: from phenomenology to treatment. Tremor Other Hyperkinet Mov (N Y). 2013;3:tre-03-161-4138-1. doi:10.7916/D88P5Z71